From Research to Clinical Practice
Is your doctor reading current research? Are they relying on medical associations for published guidelines in order to guide their clinical decisions? Are those decision makers reading current research? How much of a role do pharmaceutical companies play in creating these guidelines?
These are all important questions to ask. Most parents, patients and practitioners don't know the statistic that it takes on average 17 years for information and knowledge gained through research to be applied to clinical practice. (Brownson, et al, 2006) When working to help children we don't have 17 years. It's important that your doctor have their finger on the pulse of ongoing and newly published research.
Dr. Peirson does just that. Not only does she see new research the day it's published, she's also in touch with researchers around the country and around the world, having conversations about the very biochemistry we're all trying to better understand.
We will be updating this research library often, adding new and older research that supports the work we do to help optimize the health of your child. Use the links below or the links in the drop down menu to find studies that support the biomedical treatment of children with special needs.
These are all important questions to ask. Most parents, patients and practitioners don't know the statistic that it takes on average 17 years for information and knowledge gained through research to be applied to clinical practice. (Brownson, et al, 2006) When working to help children we don't have 17 years. It's important that your doctor have their finger on the pulse of ongoing and newly published research.
Dr. Peirson does just that. Not only does she see new research the day it's published, she's also in touch with researchers around the country and around the world, having conversations about the very biochemistry we're all trying to better understand.
We will be updating this research library often, adding new and older research that supports the work we do to help optimize the health of your child. Use the links below or the links in the drop down menu to find studies that support the biomedical treatment of children with special needs.
Search the library by using crtl + f on your keyboard or use "find in page" on your mobile device.
Biochemical Individuality
The importance of understanding individual differences in Down syndrome - Annette Karmiloff-Smith , Tamara Al-Janabi , Hana D'Souza , Jurgen Groet , Esha Massand , Kin Mok , Carla Startin , Elizabeth Fisher , John Hardy , Dean Nizetic , Victor Tybulewicz , Andre Strydom
A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment - Michael S.C. Thomas, Olatz Ojinaga Alfageme, Hana D’Souzaa, Prachi A.Patkee. Mary A.Rutherford. Kin Y.Mok, John Hardy, Annette Karmiloff-Smith, the LonDownS Consortium
Beyond Trisomy 21: Phenotypic Variability in People with Down Syndrome Explained by Further Chromosome Mis-segregation and Mosaic Aneuploidy - Huntington Potter
Same Genetic Mutation, Different Genetic Disease Phenotype - Ingrid Lobo, Ph.D.
Natural Gene-Expression Variation in Down Syndrome Modulates the Outcome of Gene-Dosage Imbalance - Paola Prandini, Samuel Deutsch, Robert Lyle, Maryline Gagnebin, Celine Delucinge Vivier, Mauro Delorenzi, Corinne Gehrig, Patrick Descombes, Stephanie Sherman, Franca Dagna Bricarelli, Chiara Baldo, Antonio Novelli, Bruno Dallapiccola, and Stylianos E. Antonarakis
Classification of Human Chromosome 21 Gene-Expression Variations in Down Syndrome: Impact on Disease Phenotypes - E. Aıt Yahya-Graison, J. Aubert, L. Dauphinot, I. Rivals, M. Prieur, G. Golfier, J. Rossier, L. Personnaz, N. Cre´au, H. Ble´haut, S. Robin, J. M. Delabar, and M.-C. Potier
Understanding the Basis for Down Syndrome Phenotypes - Randall J. Roper, Roger H. Reeves
Genetic Mechanisms Involved in the Phenotype of Down Syndrome - David Patterson
Differential gene expression studies to explore the molecular pathophysiology of Down syndrome - Stylianos E. Antonarakis, Robert Lyle, Roman Chrast, Hamish S. Scott
CHROMOSOME 21 AND DOWN SYNDROME: FROM GENOMICS TO PATHOPHYSIOLOGY - Stylianos E. Antonarakis, Robert Lyle, Emmanouil T. Dermitzakis, Alexandre Reymond and Samuel Deutsch
Systems Biology - Metabonomics - Jeremy K. Nicholson and John C. Lindon
Metabolomics and Metabonomics - Jeremy J. Ramsden
Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders - I. De Toma, L. Manubens Gil, S. Ossowski, and M. Dierssen
Trisomy of human chromosome 21 enhances amyloid-b deposition independently of an extra copy of APP - Frances K. Wiseman, Laura J. Pulford, Chris Barkus, Fan Liao, Erik Portelius, Robin Webb, Lucia Cha´vez-Gutie´rrez, Karen Cleverley, Sue Noy, Olivia Sheppard, Toby Collins, Caroline Powell, Claire J. Sarell, Matthew Rickman, Xun Choong, Justin L. Tosh, Carlos Siganporia, Heather T. Whittaker, Floy Stewart, Maria Szaruga, Michael P. Murphy, Kaj Blennow, Bart de Strooper, Henrik Zetterberg, David Bannerman, David M. Holtzman, Victor L. J. Tybulewicz and Elizabeth M. C. Fisher
Regular trisorny 21 not accompanied by increased copper-zinc superoxide dismutase (SOD1) activity - ANNA JEZIOROWSKA, LUCJUSZ JAKUBOWSKI~, JOANNA LACH AND BOGDAN KAhJZEWSKl
Increased superoxide dismutase and Down’s syndrome - J. F. Turrens
A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment - Michael S.C. Thomas, Olatz Ojinaga Alfageme, Hana D’Souzaa, Prachi A.Patkee. Mary A.Rutherford. Kin Y.Mok, John Hardy, Annette Karmiloff-Smith, the LonDownS Consortium
Beyond Trisomy 21: Phenotypic Variability in People with Down Syndrome Explained by Further Chromosome Mis-segregation and Mosaic Aneuploidy - Huntington Potter
Same Genetic Mutation, Different Genetic Disease Phenotype - Ingrid Lobo, Ph.D.
Natural Gene-Expression Variation in Down Syndrome Modulates the Outcome of Gene-Dosage Imbalance - Paola Prandini, Samuel Deutsch, Robert Lyle, Maryline Gagnebin, Celine Delucinge Vivier, Mauro Delorenzi, Corinne Gehrig, Patrick Descombes, Stephanie Sherman, Franca Dagna Bricarelli, Chiara Baldo, Antonio Novelli, Bruno Dallapiccola, and Stylianos E. Antonarakis
Classification of Human Chromosome 21 Gene-Expression Variations in Down Syndrome: Impact on Disease Phenotypes - E. Aıt Yahya-Graison, J. Aubert, L. Dauphinot, I. Rivals, M. Prieur, G. Golfier, J. Rossier, L. Personnaz, N. Cre´au, H. Ble´haut, S. Robin, J. M. Delabar, and M.-C. Potier
Understanding the Basis for Down Syndrome Phenotypes - Randall J. Roper, Roger H. Reeves
Genetic Mechanisms Involved in the Phenotype of Down Syndrome - David Patterson
Differential gene expression studies to explore the molecular pathophysiology of Down syndrome - Stylianos E. Antonarakis, Robert Lyle, Roman Chrast, Hamish S. Scott
CHROMOSOME 21 AND DOWN SYNDROME: FROM GENOMICS TO PATHOPHYSIOLOGY - Stylianos E. Antonarakis, Robert Lyle, Emmanouil T. Dermitzakis, Alexandre Reymond and Samuel Deutsch
Systems Biology - Metabonomics - Jeremy K. Nicholson and John C. Lindon
Metabolomics and Metabonomics - Jeremy J. Ramsden
Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders - I. De Toma, L. Manubens Gil, S. Ossowski, and M. Dierssen
Trisomy of human chromosome 21 enhances amyloid-b deposition independently of an extra copy of APP - Frances K. Wiseman, Laura J. Pulford, Chris Barkus, Fan Liao, Erik Portelius, Robin Webb, Lucia Cha´vez-Gutie´rrez, Karen Cleverley, Sue Noy, Olivia Sheppard, Toby Collins, Caroline Powell, Claire J. Sarell, Matthew Rickman, Xun Choong, Justin L. Tosh, Carlos Siganporia, Heather T. Whittaker, Floy Stewart, Maria Szaruga, Michael P. Murphy, Kaj Blennow, Bart de Strooper, Henrik Zetterberg, David Bannerman, David M. Holtzman, Victor L. J. Tybulewicz and Elizabeth M. C. Fisher
Regular trisorny 21 not accompanied by increased copper-zinc superoxide dismutase (SOD1) activity - ANNA JEZIOROWSKA, LUCJUSZ JAKUBOWSKI~, JOANNA LACH AND BOGDAN KAhJZEWSKl
Increased superoxide dismutase and Down’s syndrome - J. F. Turrens
Thiamine
Thiamine - Derrick Lonsdale, M.D.
The Role of Thiamin in High Calorie Malnutrition - Derrick Lonsdale
The role of thiamine in autism - Khanh vinh quốc Lươn , Lan Thi Hoàng Nguyễn
Thiamine and magnesium deficiencies: Keys to disease - D. Lonsdale
The multifaceted and widespread pathology of magnesium deficiency - S. Johnson
Dysautonomia, A Heuristic Approach to a Revised Model for Etiology of Disease - Derrick Lonsdale
Update of Cell Damage Mechanisms in Thiamine Deficiency: Focus on Oxidative Stress, Excitotoxicity and Inflammation - Alan S. Hazell∗ and Roger F. Butterworth
Vitamin B1 (thiamine) and dementia - Gary E. Gibson1, Joseph A. Hirsch, Pasquale Fonzetti, Barry D. Jordon, Rosanna T. Cirio, and Jessica Elder
Long-Term Cognitive Improvement After Benfotiamine Administration in Patients with Alzheimer’s Disease - Xiaoli Pan, Zhichun Chen, Guoqiang Fei, Shumei Pan, Weiqi Bao, Shuhua Ren, Yihui Guan, Chunjiu Zhong
Therapeutic potential of benfotiamine and its molecular targets - V. Raj , S. Ojha, F.C. Howarth , P.D. Belue, S.B. Subramanya
Benfotiamine and Cognitive Decline in Alzheimer’s Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial - Gary E. Gibsona, José A. Luchsingerc, Rosanna Ciriob, Huanlian Chenb, Jessica Franchino-Elderb, Joseph A. Hirschb, Lucien Bettendorfff, Zhengming Cheng, Sarah A. Flowersh, Linda M. Gerberg, Thomas Grandvilled, Nicole Schupfi, Hui Xub, Yaakov Sternj, Christian Habeckk, Barry Jordanl, Pasquale Fonzettin
Thiamine Deficiency Induced Dietary Disparity Promotes Oxidative Stress and Neurodegeneration - Anisha Chauhan, Nidhi Srivastva, Parvesh Bubber
Thiamine Deficiency in Childhood With Attention to Genetic Causes: Survival and Outcome Predictors - Juan Darıo Ortigoza-Escobar, MD, PhD, Majid Alfadhel, MD, Marta Molero-Luis, PhD, Niklas Darin, MD, PhD, Ronen Spiegel, MD, Irenaeus F. de Coo, MD, Mike Gerards, PhD, Robert W. Taylor, MD, PhD, Rafael Artuch, MD, PhD, Marwan Nashabat, MD, Pilar Rodrıguez-Pombo, PhD, Brahim Tabarki, MD, Belen P erez-Due nas, MD, PhD
Down's Syndrome and Thiamine Deficiency - Christopher M. Reading, B.Sc., M.B. B.S., M.R.A.N2.C.P., Alan McLeay, M.B. B.S., and Silvia Nobiie, Ph.D.
Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide - Derrick Lonsdale, Raymond J.
Shamberger & Tapan Audhya
Etiology and therapeutic approach to elevated lactate - Lars W. Andersen, BS, Julie Mackenhauer, MD, Jonathan C. Roberts, MD, Katherine M. Berg, MD, Michael N. Cocchi, MD, and Michael W. Donnino, MD
Pediatric Beriberi Clinical Presentation - Simon S Rabinowitz, MD, PhD, FAAP; Chief Editor: Jatinder Bhatia, MBBS, FAAP
The Pivotal Role of Aldehyde Toxicity in Autism Spectrum Disorder: The Therapeutic Potential of Micronutrient Supplementation - Frances Jurnak
New Considerations on the Neuromodulatory Role of Thiamine - Joseph A. Hirsch James Parrott
The pyruvate dehydrogenase complex as a therapeutic target for age-related diseases - Peter W. Stacpoole
A Role for Thiamine in the Regulation of Fatty Acid and Cholesterol Biosynthesis in Cultured Cells of Neural Origin - J. J. VOLPE and J. C. MARASA
Thiamine Deficiency and Delirium - KENNETH OSIEZAGHA, MD; SHAHID ALI, MD; C. FREEMAN, MD; NARVIAR C. BARKER, PhD; SHAGUFTA JABEEN, MD; SARBANI MAITRA, MD; YETUNDE OLAGBEMIRO, MD; WILLIAM RICHIE, MD, FAPA; and RAHN K. BAILEY, MD, FAPA
Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults - Shibani Dhir, Maya Tarasenko, Eleonora Napoli and Cecilia Giulivi
Lactic Acidosis: A Lesser Known Side Effect of Thiamine Deficiency - Carol Rees Parrish, M.S., R.D.
The Role of Thiamin in High Calorie Malnutrition - Derrick Lonsdale
The role of thiamine in autism - Khanh vinh quốc Lươn , Lan Thi Hoàng Nguyễn
Thiamine and magnesium deficiencies: Keys to disease - D. Lonsdale
The multifaceted and widespread pathology of magnesium deficiency - S. Johnson
Dysautonomia, A Heuristic Approach to a Revised Model for Etiology of Disease - Derrick Lonsdale
Update of Cell Damage Mechanisms in Thiamine Deficiency: Focus on Oxidative Stress, Excitotoxicity and Inflammation - Alan S. Hazell∗ and Roger F. Butterworth
Vitamin B1 (thiamine) and dementia - Gary E. Gibson1, Joseph A. Hirsch, Pasquale Fonzetti, Barry D. Jordon, Rosanna T. Cirio, and Jessica Elder
Long-Term Cognitive Improvement After Benfotiamine Administration in Patients with Alzheimer’s Disease - Xiaoli Pan, Zhichun Chen, Guoqiang Fei, Shumei Pan, Weiqi Bao, Shuhua Ren, Yihui Guan, Chunjiu Zhong
Therapeutic potential of benfotiamine and its molecular targets - V. Raj , S. Ojha, F.C. Howarth , P.D. Belue, S.B. Subramanya
Benfotiamine and Cognitive Decline in Alzheimer’s Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial - Gary E. Gibsona, José A. Luchsingerc, Rosanna Ciriob, Huanlian Chenb, Jessica Franchino-Elderb, Joseph A. Hirschb, Lucien Bettendorfff, Zhengming Cheng, Sarah A. Flowersh, Linda M. Gerberg, Thomas Grandvilled, Nicole Schupfi, Hui Xub, Yaakov Sternj, Christian Habeckk, Barry Jordanl, Pasquale Fonzettin
Thiamine Deficiency Induced Dietary Disparity Promotes Oxidative Stress and Neurodegeneration - Anisha Chauhan, Nidhi Srivastva, Parvesh Bubber
Thiamine Deficiency in Childhood With Attention to Genetic Causes: Survival and Outcome Predictors - Juan Darıo Ortigoza-Escobar, MD, PhD, Majid Alfadhel, MD, Marta Molero-Luis, PhD, Niklas Darin, MD, PhD, Ronen Spiegel, MD, Irenaeus F. de Coo, MD, Mike Gerards, PhD, Robert W. Taylor, MD, PhD, Rafael Artuch, MD, PhD, Marwan Nashabat, MD, Pilar Rodrıguez-Pombo, PhD, Brahim Tabarki, MD, Belen P erez-Due nas, MD, PhD
Down's Syndrome and Thiamine Deficiency - Christopher M. Reading, B.Sc., M.B. B.S., M.R.A.N2.C.P., Alan McLeay, M.B. B.S., and Silvia Nobiie, Ph.D.
Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide - Derrick Lonsdale, Raymond J.
Shamberger & Tapan Audhya
Etiology and therapeutic approach to elevated lactate - Lars W. Andersen, BS, Julie Mackenhauer, MD, Jonathan C. Roberts, MD, Katherine M. Berg, MD, Michael N. Cocchi, MD, and Michael W. Donnino, MD
Pediatric Beriberi Clinical Presentation - Simon S Rabinowitz, MD, PhD, FAAP; Chief Editor: Jatinder Bhatia, MBBS, FAAP
The Pivotal Role of Aldehyde Toxicity in Autism Spectrum Disorder: The Therapeutic Potential of Micronutrient Supplementation - Frances Jurnak
New Considerations on the Neuromodulatory Role of Thiamine - Joseph A. Hirsch James Parrott
The pyruvate dehydrogenase complex as a therapeutic target for age-related diseases - Peter W. Stacpoole
A Role for Thiamine in the Regulation of Fatty Acid and Cholesterol Biosynthesis in Cultured Cells of Neural Origin - J. J. VOLPE and J. C. MARASA
Thiamine Deficiency and Delirium - KENNETH OSIEZAGHA, MD; SHAHID ALI, MD; C. FREEMAN, MD; NARVIAR C. BARKER, PhD; SHAGUFTA JABEEN, MD; SARBANI MAITRA, MD; YETUNDE OLAGBEMIRO, MD; WILLIAM RICHIE, MD, FAPA; and RAHN K. BAILEY, MD, FAPA
Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults - Shibani Dhir, Maya Tarasenko, Eleonora Napoli and Cecilia Giulivi
Lactic Acidosis: A Lesser Known Side Effect of Thiamine Deficiency - Carol Rees Parrish, M.S., R.D.
Riboflavin
Riboflavin Has Neuroprotective Potential: Focus on Parkinson’s Disease and Migraine - Eyad T. Marashly* and Saeed A. Bohlega
Riboflavin Responsive Mitochondrial Dysfunction in Neurodegenerative Diseases - Tamilarasan Udhayabanu, Andreea Manole, Mohan Rajeshwari, Perumal Varalakshmi, Henry Houlden and Balasubramaniem Ashokkumar
Riboflavin Deficiency—Implications for General Human Health and Inborn Errors of Metabolism - Signe Mosegaard, Graziana Dipace, Peter Bross, Jasper Carlsen, Niels Gregersen and Rikke Katrine Jentoft Olsen
Riboflavin (vitamin B-2) and health - Hilary J Powers
Riboflavin - Alternative Medicine Review Volume 13, Number 4 2008
Riboflavin - John T. Pinto
Riboflavin Deficiency - Aakriti Bhusal1; Stephen W. Banks.
Riboflavin: The Health Benefits of a Forgotten Natural Vitamin - Nittiya Suwannasom, Ijad Kao, Axel Pruß, Radostina Georgieva and Hans Bäumler
Progress in phototherapy - Maria Cristina Korbage de Araujo, Flavio Adolfo Costa Vaz, Jose Lauro Araujo Ramos
Phototherapy in the newborn: what’s new? - Murat Yurdakök
Treatable childhood neuronopathy caused by mutations in riboflavin transporter RFVT2 - A. Reghan Foley, et.al.
Clinical presentation and outcome of riboflavin transporter deficiency: mini review after five years of experience - Bregje Jaeger1 & Annet M. Bosch
Bile Salt Enhancement of Riboflavin and Flavin Mononucleotide Absorption in Man - Michael Mayerjohn, Stuart Feldman, and Milo Gibaldi
Neuropsychiatric manifestations of defect in mitochondrial beta oxidation response to riboflavin - William J Triggs, Charles R Roe, William J Rhead, Sandra K Hanson, Shen-Nan Lin, L James Willmore
Riboflavin (vitamin B2) and oxidative stress: a review - Marziyeh Ashoori and Ahmad Saedisomeolia
Vitamin responsive bulbar palsy in an infant - Riaz Ahmed
From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of Vitamin D - John T. Pinto and Arthur J. L. Cooper
Emerging Roles for Riboflavin in Functional Rescue of Mitochondrial Beta-Oxidation Flavoenzymes - Bárbara J. Henriques, Rikke K. Olsen, Peter Bross and Cláudio M. Gomes
Riboflavin: The Health Benefits of a Forgotten Natural Vitamin - Nittiya Suwannasom 1,2 , Ijad Kao 1 , Axel Pruß 1 , Radostina Georgieva 1,3 and Hans Bäumler
Persistent Lactic Acidosis in an 18-month-old Girl Status Post Bone Marrow Transplant - Chaya N. Murali, MD, Rebecca Ganetzky, MD
Riboflavin Responsive Mitochondrial Dysfunction in Neurodegenerative Diseases - Tamilarasan Udhayabanu, Andreea Manole, Mohan Rajeshwari, Perumal Varalakshmi, Henry Houlden and Balasubramaniem Ashokkumar
Riboflavin Deficiency—Implications for General Human Health and Inborn Errors of Metabolism - Signe Mosegaard, Graziana Dipace, Peter Bross, Jasper Carlsen, Niels Gregersen and Rikke Katrine Jentoft Olsen
Riboflavin (vitamin B-2) and health - Hilary J Powers
Riboflavin - Alternative Medicine Review Volume 13, Number 4 2008
Riboflavin - John T. Pinto
Riboflavin Deficiency - Aakriti Bhusal1; Stephen W. Banks.
Riboflavin: The Health Benefits of a Forgotten Natural Vitamin - Nittiya Suwannasom, Ijad Kao, Axel Pruß, Radostina Georgieva and Hans Bäumler
Progress in phototherapy - Maria Cristina Korbage de Araujo, Flavio Adolfo Costa Vaz, Jose Lauro Araujo Ramos
Phototherapy in the newborn: what’s new? - Murat Yurdakök
Treatable childhood neuronopathy caused by mutations in riboflavin transporter RFVT2 - A. Reghan Foley, et.al.
Clinical presentation and outcome of riboflavin transporter deficiency: mini review after five years of experience - Bregje Jaeger1 & Annet M. Bosch
Bile Salt Enhancement of Riboflavin and Flavin Mononucleotide Absorption in Man - Michael Mayerjohn, Stuart Feldman, and Milo Gibaldi
Neuropsychiatric manifestations of defect in mitochondrial beta oxidation response to riboflavin - William J Triggs, Charles R Roe, William J Rhead, Sandra K Hanson, Shen-Nan Lin, L James Willmore
Riboflavin (vitamin B2) and oxidative stress: a review - Marziyeh Ashoori and Ahmad Saedisomeolia
Vitamin responsive bulbar palsy in an infant - Riaz Ahmed
From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of Vitamin D - John T. Pinto and Arthur J. L. Cooper
Emerging Roles for Riboflavin in Functional Rescue of Mitochondrial Beta-Oxidation Flavoenzymes - Bárbara J. Henriques, Rikke K. Olsen, Peter Bross and Cláudio M. Gomes
Riboflavin: The Health Benefits of a Forgotten Natural Vitamin - Nittiya Suwannasom 1,2 , Ijad Kao 1 , Axel Pruß 1 , Radostina Georgieva 1,3 and Hans Bäumler
Persistent Lactic Acidosis in an 18-month-old Girl Status Post Bone Marrow Transplant - Chaya N. Murali, MD, Rebecca Ganetzky, MD
Vitamins
Role of vitamins in gastrointestinal diseases - Omar A Masri, Jean M Chalhoub, Ala I Sharara
Nutritional Neuropathies - Nancy Hammond, MD, Yunxia Wang, MD, Mazen Dimachkie, MD, and Richard Barohn, MD
Blepharospasm and vitamin B12 deficiency - Bengt Edvardsson, Staffan Persson
Vitamins for Chronic Disease Prevention in Adults - Robert H. Fletcher, MD, MSc and Kathleen M. Fairfield, MD, DrPH
B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review - David O. Kennedy
B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin - Carlos Alberto Calderón‐Ospina and Mauricio Orlando Nava‐Mesa
The Effect of Combined Vitamin B Therapy on the Outcome of Diabetic Isolated Abducent Nerve Palsy - Sherif Ahmed Kamel Amer
Vitamin Deficiencies: An Overview - Olivier Wenker, MD
Skin findings associated with nutritional deficiencies - Fabrizio Galimberti, MD, PhD and Natasha A. Mesinkovska, MD, PhD
Role of various vitamins in the patients with epilepsy - Mohammad Asif
Effect of a vitamin/mineral supplement on children and adults with autism - James B Adams, Tapan Audhya, Sharon McDonough-Means, Robert A Rubin, David Quig, Elizabeth Geis, Eva Gehn, Melissa Loresto, Jessica Mitchell, Sharon Atwood, Suzanne Barnhouse and Wondra Lee
Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial - RE Frye1, J Slattery, L Delhey, B Furgerson, T Strickland, M Tippett, A Sailey, R Wynne, S Rose, S Melnyk, S Jill James, JM Sequeira and EV Quadros
Magnesium Vit B6 intake reduces central nervous system hyperexcitability in children. - Mousain-Bosc M, Roche M, Rapin J, Bali JP.
Vitamin D in Children’s Health - Joy A. Weydert
Nutrition and Functional Neurochemistry - Gary E Gibson and John P Blass
Pediatric Pellagra - Simon S Rabinowitz, MD, PhD, FAAP; Chief Editor: Jatinder Bhatia, MBBS, FAAP
Pellegra and its prevention and control in major emergencies - World Health Organization, 2000
Elevated Vitamin B12 Blood Levels - Georges Mouton MD
Role of Magnesium in the Regulation of Hepatic Glucose Homeostasis - Chesinta Voma and Andrea M.P. Romani
High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased Km): relevance to genetic disease and polymorphisms - Bruce N Ames, Ilan Elson-Schwab, and Eli A Silver
Vitamin effects on the immune system: vitamins A and D take centre stage - J. Rodrigo Mora, Makoto Iwata, and Ulrich H. von Andrian
Vitamins and Nutrients as Primary Treatments in Experimental Brain Injury: Clinical Implications for Nutraceutical Therapies - Cole Vonder Haar, Todd C. Peterson, Kris M. Martens, and Michael R. Hoane
Cutaneous manifestations of nutritional deficiency - Michelle L. Heatha and Robert Sidbury
Nutritional Neuropathies - Nancy Hammond, MD, Yunxia Wang, MD, Mazen Dimachkie, MD, and Richard Barohn, MD
Blepharospasm and vitamin B12 deficiency - Bengt Edvardsson, Staffan Persson
Vitamins for Chronic Disease Prevention in Adults - Robert H. Fletcher, MD, MSc and Kathleen M. Fairfield, MD, DrPH
B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review - David O. Kennedy
B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin - Carlos Alberto Calderón‐Ospina and Mauricio Orlando Nava‐Mesa
The Effect of Combined Vitamin B Therapy on the Outcome of Diabetic Isolated Abducent Nerve Palsy - Sherif Ahmed Kamel Amer
Vitamin Deficiencies: An Overview - Olivier Wenker, MD
Skin findings associated with nutritional deficiencies - Fabrizio Galimberti, MD, PhD and Natasha A. Mesinkovska, MD, PhD
Role of various vitamins in the patients with epilepsy - Mohammad Asif
Effect of a vitamin/mineral supplement on children and adults with autism - James B Adams, Tapan Audhya, Sharon McDonough-Means, Robert A Rubin, David Quig, Elizabeth Geis, Eva Gehn, Melissa Loresto, Jessica Mitchell, Sharon Atwood, Suzanne Barnhouse and Wondra Lee
Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial - RE Frye1, J Slattery, L Delhey, B Furgerson, T Strickland, M Tippett, A Sailey, R Wynne, S Rose, S Melnyk, S Jill James, JM Sequeira and EV Quadros
Magnesium Vit B6 intake reduces central nervous system hyperexcitability in children. - Mousain-Bosc M, Roche M, Rapin J, Bali JP.
Vitamin D in Children’s Health - Joy A. Weydert
Nutrition and Functional Neurochemistry - Gary E Gibson and John P Blass
Pediatric Pellagra - Simon S Rabinowitz, MD, PhD, FAAP; Chief Editor: Jatinder Bhatia, MBBS, FAAP
Pellegra and its prevention and control in major emergencies - World Health Organization, 2000
Elevated Vitamin B12 Blood Levels - Georges Mouton MD
Role of Magnesium in the Regulation of Hepatic Glucose Homeostasis - Chesinta Voma and Andrea M.P. Romani
High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased Km): relevance to genetic disease and polymorphisms - Bruce N Ames, Ilan Elson-Schwab, and Eli A Silver
Vitamin effects on the immune system: vitamins A and D take centre stage - J. Rodrigo Mora, Makoto Iwata, and Ulrich H. von Andrian
Vitamins and Nutrients as Primary Treatments in Experimental Brain Injury: Clinical Implications for Nutraceutical Therapies - Cole Vonder Haar, Todd C. Peterson, Kris M. Martens, and Michael R. Hoane
Cutaneous manifestations of nutritional deficiency - Michelle L. Heatha and Robert Sidbury
Minerals
Neuroprotective action of lithium in disorders of the central nervous system - Chi-Tso CHIU and De-Maw CHUANG
Lithium as a Nutrient - Timothy M. Marshall, Ph.D.
Inflammation and impulsivity: Is lithium the chill-pill? - Milena Girotti
Reversal of cognitive decline: A novel therapeutic program - Dale E. Bredesen
Zinc, Carnosine, and Neurodegenerative Diseases - Masahiro Kawahara, Ken-ichiro Tanaka and Midori Kato-Negishi
Copper and Zinc, Biological Role and Significance of Copper/Zinc Imbalance - Josko Osredkar and Natasa Sustar
Dietary Reference Intakes for Vitamin A, Vitamin K, ARsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molydenum, Nickel, Silicon, Vanadium, and Zinc - A Report of the Panel on Micronutrients
Long-term Brain and Behavioral Consequences of Early Iron Deficiency - Michael K. Georgieff, MD
Role of manganese in neurodegenerative diseases - Aaron B. Bowman, Gunnar F. Kwakye, Elena Herrero Hernández, and Michael Aschner
Manganese and Lipid Metabolism as Affected by Dietary Manganese and Fat - Jan M. Johnson and Constance Kies
Zinc and gastrointestinal disease - Sonja Skrovanek, Katherine DiGuilio, Robert Bailey, William Huntington, Ryan Urbas, Barani Mayilvaganan, Giancarlo Mercogliano, James M Mullin
Selenium and the thyroid - Josef Köhrle
Hair Mineral and Trace Element Content in Children with Down’s Syndrome - Andrey R. Grabeklis1,2 & Anatoly V. Skalny1,2,3 & Anastasia A. Skalnaya4 & Irina V. Zhegalova2 & Svetlana V. Notova5,6 & Anna L. Mazaletskaya1 & Margarita G. Skalnaya1,2 & Alexey A. Tinkov
Iron Biology in Immune Function, Muscle Metabolism and Neuronal Functioning - John L. Beard
The Nutritional Relationships of Iron - David L. Watts, Ph.D., F.A.C.E.P.1
Copper: Toxicological relevance and mechanisms - Lisa M. Gaetke, Hannah S. Chow-Johnson, and Ching K. Chow
Copper absorption and bioavailability - Raul A Wapnir
Lithium as a Nutrient - Timothy M. Marshall, Ph.D.
Inflammation and impulsivity: Is lithium the chill-pill? - Milena Girotti
Reversal of cognitive decline: A novel therapeutic program - Dale E. Bredesen
Zinc, Carnosine, and Neurodegenerative Diseases - Masahiro Kawahara, Ken-ichiro Tanaka and Midori Kato-Negishi
Copper and Zinc, Biological Role and Significance of Copper/Zinc Imbalance - Josko Osredkar and Natasa Sustar
Dietary Reference Intakes for Vitamin A, Vitamin K, ARsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molydenum, Nickel, Silicon, Vanadium, and Zinc - A Report of the Panel on Micronutrients
Long-term Brain and Behavioral Consequences of Early Iron Deficiency - Michael K. Georgieff, MD
Role of manganese in neurodegenerative diseases - Aaron B. Bowman, Gunnar F. Kwakye, Elena Herrero Hernández, and Michael Aschner
Manganese and Lipid Metabolism as Affected by Dietary Manganese and Fat - Jan M. Johnson and Constance Kies
Zinc and gastrointestinal disease - Sonja Skrovanek, Katherine DiGuilio, Robert Bailey, William Huntington, Ryan Urbas, Barani Mayilvaganan, Giancarlo Mercogliano, James M Mullin
Selenium and the thyroid - Josef Köhrle
Hair Mineral and Trace Element Content in Children with Down’s Syndrome - Andrey R. Grabeklis1,2 & Anatoly V. Skalny1,2,3 & Anastasia A. Skalnaya4 & Irina V. Zhegalova2 & Svetlana V. Notova5,6 & Anna L. Mazaletskaya1 & Margarita G. Skalnaya1,2 & Alexey A. Tinkov
Iron Biology in Immune Function, Muscle Metabolism and Neuronal Functioning - John L. Beard
The Nutritional Relationships of Iron - David L. Watts, Ph.D., F.A.C.E.P.1
Copper: Toxicological relevance and mechanisms - Lisa M. Gaetke, Hannah S. Chow-Johnson, and Ching K. Chow
Copper absorption and bioavailability - Raul A Wapnir
Amino Acids
Review: Taurine: A “very essential” amino acid - Harris Ripps, Wen Shen
Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review - Meerza Abdul Razak, Pathan Shajahan Begum, Buddolla Viswanath and Senthilkumar Rajagopal
Arginine metabolism and nutrition in growth, health and disease - Guoyao Wu, Fuller W. Bazer, Teresa A. Davis, Sung Woo Kim, Peng Li, J. Marc Rhoads, M. Carey Satterfield, Stephen B. Smith, Thomas E. Spencer, and Yulong Yin
A Primer on Branched Chain Amino Acids - Starkie Sowers, CN
Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review - Meerza Abdul Razak, Pathan Shajahan Begum, Buddolla Viswanath and Senthilkumar Rajagopal
Arginine metabolism and nutrition in growth, health and disease - Guoyao Wu, Fuller W. Bazer, Teresa A. Davis, Sung Woo Kim, Peng Li, J. Marc Rhoads, M. Carey Satterfield, Stephen B. Smith, Thomas E. Spencer, and Yulong Yin
A Primer on Branched Chain Amino Acids - Starkie Sowers, CN
Choline
Health effects of dietary phospholipids - Daniela Küllenberg, Lenka A Taylor, Michael Schneider and Ulrich Massing
Neuroprotective Actions of Dietary Choline - Jan Krzysztof Blusztajn *, Barbara E. Slack and Tiffany J. Mellott
Choline: An Essential Nutrient for Public Health - Steven H. Zeisel, M.D., Ph.D. and Kerry-Ann da Costa, Ph.D.
Source of the Acetyl Group in Acetylcholine - J. H. Quastel
Choline deficiency increases lymphocyte apoptosis and DNA damage in humans - Kerry-Ann da Costa, Mihai D Niculescu, Corneliu N Craciunescu, Leslie M Fischer, and Steven H Zeisel
Studies on the Metabolic Pathway of the Acetyl Group for Acetylcholine Synthesis - Gary E. Gibson and Masahisa Shimada
Choline: Critical Role During Fetal Development and Dietary Requirements in Adults - Steven H. Zeisel
Choline Metabolites: Gene by Diet Interactions - Tangi Smallwood, Hooman Allayee, and Brian J. Bennett
Maternal choline supplementation: A potential prenatal treatment for Down syndrome and Alzheimer’s disease - Barbara J. Strupp1, Brian E. Powers1, Ramon Velazquez, Jessica A. Ash, Christy M. Kelley, Melissa J. Alldred, Myla Strawderman, Marie A. Caudill, Elliott J. Mufson and Stephen D. Ginsberg
Maternal choline supplementation in a mouse model of Down syndrome: effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring - Brian E. Powers, Christy M. Kelley, Ramon Velazquez, Jessica A. Ash, Myla S. Strawderman, Melissa J. Alldred, Stephen D. Ginsbergd, Elliott J. Mufson, and Barbara J. Strupp
Choline’s role in maintaining liver function: new evidence for epigenetic mechanisms - Mihai G. Mehedint and Steven H. Zeisel
The nutritional burden of methylation reactions - Robert F. Bertolo and Laura E. McBreairty
Neuroprotective Actions of Dietary Choline - Jan Krzysztof Blusztajn *, Barbara E. Slack and Tiffany J. Mellott
Choline: An Essential Nutrient for Public Health - Steven H. Zeisel, M.D., Ph.D. and Kerry-Ann da Costa, Ph.D.
Source of the Acetyl Group in Acetylcholine - J. H. Quastel
Choline deficiency increases lymphocyte apoptosis and DNA damage in humans - Kerry-Ann da Costa, Mihai D Niculescu, Corneliu N Craciunescu, Leslie M Fischer, and Steven H Zeisel
Studies on the Metabolic Pathway of the Acetyl Group for Acetylcholine Synthesis - Gary E. Gibson and Masahisa Shimada
Choline: Critical Role During Fetal Development and Dietary Requirements in Adults - Steven H. Zeisel
Choline Metabolites: Gene by Diet Interactions - Tangi Smallwood, Hooman Allayee, and Brian J. Bennett
Maternal choline supplementation: A potential prenatal treatment for Down syndrome and Alzheimer’s disease - Barbara J. Strupp1, Brian E. Powers1, Ramon Velazquez, Jessica A. Ash, Christy M. Kelley, Melissa J. Alldred, Myla Strawderman, Marie A. Caudill, Elliott J. Mufson and Stephen D. Ginsberg
Maternal choline supplementation in a mouse model of Down syndrome: effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring - Brian E. Powers, Christy M. Kelley, Ramon Velazquez, Jessica A. Ash, Myla S. Strawderman, Melissa J. Alldred, Stephen D. Ginsbergd, Elliott J. Mufson, and Barbara J. Strupp
Choline’s role in maintaining liver function: new evidence for epigenetic mechanisms - Mihai G. Mehedint and Steven H. Zeisel
The nutritional burden of methylation reactions - Robert F. Bertolo and Laura E. McBreairty
Diet
Adolescence: Does good nutrition = good behaviour? - Bernard Gesch
Dietary Intakes and Nutritional Issues in Neurologically Impaired Children - Francesca Penagini, Chiara Mameli, Valentina Fabiano, Domenica Brunetti, Dario Dilillo and Gian Vincenzo Zuccotti
Growth of children on the ketogenic diet - Eileen PG Vining, Paula Pyzik, Jane McGrogan, Heather Hladky, Akash AnandBS, Steven Kriegler, John M Freeman
Toxicology of food dyes - Sarah Kobylewski, Michael F. Jacobson
Manipulation of Host Diet To Reduce Gastrointestinal Colonization by the Opportunistic Pathogen Candida albicans - Kearney T. W. Gunsalus, Stephanie N. Tornberg-Belanger, Nirupa R. Matthan, Alice H. Lichtenstein, Carol A. Kumamoto
Low consumption of fruit and vegetables, and markers of oxidative stress in children with Down syndrome - Seyyed Mustafa Nachvak, Soltan Ali Mahboob, Tirang Reza Neyestani, Seyyed Ali Keshawarz, John R. Speakman
Diet in hidradenitis suppurativa: a review of published and lay literature - Annika Silfvast-Kaiser, MD , Ronnie Youssef, BS, and So Y. Paek, MD
Dietary Intakes and Nutritional Issues in Neurologically Impaired Children - Francesca Penagini, Chiara Mameli, Valentina Fabiano, Domenica Brunetti, Dario Dilillo and Gian Vincenzo Zuccotti
Growth of children on the ketogenic diet - Eileen PG Vining, Paula Pyzik, Jane McGrogan, Heather Hladky, Akash AnandBS, Steven Kriegler, John M Freeman
Toxicology of food dyes - Sarah Kobylewski, Michael F. Jacobson
Manipulation of Host Diet To Reduce Gastrointestinal Colonization by the Opportunistic Pathogen Candida albicans - Kearney T. W. Gunsalus, Stephanie N. Tornberg-Belanger, Nirupa R. Matthan, Alice H. Lichtenstein, Carol A. Kumamoto
Low consumption of fruit and vegetables, and markers of oxidative stress in children with Down syndrome - Seyyed Mustafa Nachvak, Soltan Ali Mahboob, Tirang Reza Neyestani, Seyyed Ali Keshawarz, John R. Speakman
Diet in hidradenitis suppurativa: a review of published and lay literature - Annika Silfvast-Kaiser, MD , Ronnie Youssef, BS, and So Y. Paek, MD
Nervous System
Disorders of Gastrointestinal Motility in Neurologic Diseases - MICHAEL CAMILLERI, M.D.
Fundamentals of Neurogastroenterology - J D Wood, D H Alpers, P L R Andrews
The neurology of enteric disease - A J Wills, D S N A Pengiran Tengah, G K T Holmes
Gastrointestinal complications after ischemic stroke - Carlos R. Camara-Lemarroy, Beatriz E. Ibarra-Yruegas, Fernando Gongora-Rivera
Nutrition and Dietary Supplements in Motor Neuron Disease - Jeffrey Rosenfeld, PhD., MD, FAANa and Amy Ellis, MPH, RD, CNSD
Central Nervous System Control of Gastrointestinal Motility and Secretion and Modulation of Gastrointestinal Functions - Kirsteen N. Browning and R. Alberto Travagli
Reduction of Movement in Neurological Diseases: Effects on Neural Stem Cells Characteristics - Raffaella Adami, Jessica Pagano, Michela Colombo, Natalia Platonova, Deborah Reccia, Raffaella Chiaramonte, Roberto Bottinelli, Monica Canepari and Daniele Bottai
The role of peripheral nerve fibers and their neurotransmitters in cartilage and bone physiology and pathophysiology - Susanne Grässel
Is Bone A Target-tissue for the Nervous System? New Advances on the Understanding of their Interactions - José M. García-Castellano, M.D., Ph.D., Pilar Díaz-Herrera, M.D., Ph.D., José A. Morcuende, M.D., Ph.D.
Bone and Brain: A Review of Neural, Hormonal, and Musculoskeletal Connections - Kevin B. Jones, M.D., Anthony V. Mollano, M.D., Jose A. Morcuende, M.D., Ph.D., Reginald R. Cooper, M.D., Charles L. Saltzman, M.D.
Control of Bone Remodeling by the Peripheral Sympathetic Nervous System - Florent Elefteriou, Preston Campbell, and Yun Ma
The Multifactorial Role of Peripheral Nervous System in Bone Growth - Ioannis Gkiatas, Dimitrios Papadopoulos, Emilios E. Pakos, Ioannis Kostas-Agnantis, Ioannis Gelalis, Marios Vekris and Anastasios Korompilias
Neurologic manifestations of malabsorption syndromes - Ronald F. Pfeiffer
Fundamentals of Neurogastroenterology - J D Wood, D H Alpers, P L R Andrews
The neurology of enteric disease - A J Wills, D S N A Pengiran Tengah, G K T Holmes
Gastrointestinal complications after ischemic stroke - Carlos R. Camara-Lemarroy, Beatriz E. Ibarra-Yruegas, Fernando Gongora-Rivera
Nutrition and Dietary Supplements in Motor Neuron Disease - Jeffrey Rosenfeld, PhD., MD, FAANa and Amy Ellis, MPH, RD, CNSD
Central Nervous System Control of Gastrointestinal Motility and Secretion and Modulation of Gastrointestinal Functions - Kirsteen N. Browning and R. Alberto Travagli
Reduction of Movement in Neurological Diseases: Effects on Neural Stem Cells Characteristics - Raffaella Adami, Jessica Pagano, Michela Colombo, Natalia Platonova, Deborah Reccia, Raffaella Chiaramonte, Roberto Bottinelli, Monica Canepari and Daniele Bottai
The role of peripheral nerve fibers and their neurotransmitters in cartilage and bone physiology and pathophysiology - Susanne Grässel
Is Bone A Target-tissue for the Nervous System? New Advances on the Understanding of their Interactions - José M. García-Castellano, M.D., Ph.D., Pilar Díaz-Herrera, M.D., Ph.D., José A. Morcuende, M.D., Ph.D.
Bone and Brain: A Review of Neural, Hormonal, and Musculoskeletal Connections - Kevin B. Jones, M.D., Anthony V. Mollano, M.D., Jose A. Morcuende, M.D., Ph.D., Reginald R. Cooper, M.D., Charles L. Saltzman, M.D.
Control of Bone Remodeling by the Peripheral Sympathetic Nervous System - Florent Elefteriou, Preston Campbell, and Yun Ma
The Multifactorial Role of Peripheral Nervous System in Bone Growth - Ioannis Gkiatas, Dimitrios Papadopoulos, Emilios E. Pakos, Ioannis Kostas-Agnantis, Ioannis Gelalis, Marios Vekris and Anastasios Korompilias
Neurologic manifestations of malabsorption syndromes - Ronald F. Pfeiffer
Microbiome/Gastrointestinal
Nutritional Consequences of Small Intestinal Bacterial Overgrowth - John K. DiBaise
Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth - Victor Chedid, MD, Bani Chander Roland, MD, Edmundo Justino, MD
The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host - Qi Hui Sam, Matthew Wook Chang, and Louis Yi Ann Chai
Oral Candidal and Streptococcal carriage in Down syndrome patients - Gouse Mohiddin, Aravindha Babu Narayanaswamy, Masthan K. M. K., Anitha Nagarajan, Abikshyeet Panda, Shyam Sundar Behura
Small intestinal bacterial overgrowth syndrome in children - Katarzyna Siniewicz-Luzeńczyk1 , Agnieszka Bik-Gawin1 , Krzysztof Zeman1 , Leokadia Bąk-Romaniszyn2
Microbiome impact on metabolism and function of sex, thyroid, growth and parathyroid hormones - Michał Kunc1, Anna Gabrych1 and Jacek M. Witkowsk
Early Disruption of the Microbiome Leading to Decreased Antioxidant Capacity and Epigenetic Changes: Implications for the Rise in Autism - Rebecca S. Eshraghi, Richard C. Deth, Rahul Mittal, Mayank Aranke, Sae-In S. Kay, Baharak Moshiree and Adrien A. Eshraghi
The microbiota–gut–brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both? - Giada De Palma, Stephen M. Collins, Premysl Bercik and Elena F. Verdu
Gut microbiota: puppeteer of the host juvenile growth - Martin Schwarzer
Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication - Esther E. Fröhlich, Aitak Farzi, Raphaela Mayerhofer, Florian Reichmann, Angela Jacan, Bernhard Wagner, Erwin Zinser, Natalie Bordag , Christoph Magnes, Eleonore Fröhlich, Karl Kashofer, Gregor Gorkiewicz, Peter Holzer
Dysbiosis, small intestinal bacterial overgrowth and biofilms in autism and chronic illness - Anju Usman Singh
Blastocystis: how do specific diets and human gut microbiota affect its development and pathogenicity? - M. Lepczyńska1 & J. Białkowska2 & E. Dzika1 & K. Piskorz-Ogórek3,4 & J. Korycińska
GI Microbiota and Regulation of the Immune System - Edited by Gary B. Huffnagle and Mairi C. Noverr
Proton Pump Inhibitor Use in Infants: FDA Reviewer Experience - Ii-Lun Chen, Wen-Yi Gao, Aisha P. Johnson, Ali Niak, John Troiani, Joyce Korvick, Nancy Snow, Kristina Estes, Amy Taylor, and Donna Griebel
Inflammation and gastrointestinal Candida colonization - Carol A. Kumamoto
Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the Dawn of the Postantibiotic Era - Maria Kostakioti, Maria Hadjifrangiskou, and Scott J. Hultgren
Reduction in Obsessive Compulsive Disorder and Self-Injurious Behavior with Saccharomyces boulardii in a Child with Autism: A Case Report - Victoria Kobliner, MS, RDN; Elizabeth Mumper, MD, FAAP, IFMCP; Sidney M. Baker, MD
Motility Problems in the Intellectually Challenged Child, Adolescent, and Young Adult - Massimo Martinelli, MD, Annamaria Staiano, MD*
The Role of Fiber in the Treatment of Functional Gastrointestinal Disorders in Children - Cara Hannah Axelrod and Miguel Saps
Autism: Metabolism, Mitochondria, and the Microbiome - Derrick MacFabe, MD
Exposure to antibiotics in the first 24 months of life and neurocognitive outcomes at 11 years of age - R. F. Slykerman & C. Coomarasamy & K. Wickens & J. M. D. Thompson & T. V. Stanley & C. Barthow & J. Kang3 & J. Crane & E. A. Mitchell
- Gerard Clarke, Roman M. Stilling1, Paul J Kennedy, Catherine Stanton, John F. Cryan, Timothy G. Dinan
The Jarisch–Herxheimer Reaction After Antibiotic Treatment of Spirochetal Infections: A Review of Recent Cases and Our Understanding of Pathogenesis - Thomas Butler
A Study of Digestive Absorption in Four Cases of Down’s Syndrome. Down’s Syndrome, Malnutrition, Malabsorption, and Alzheimer’s Disease - F. ABALAN, A. JOUAN, M. T. WEERTS, C. SOLLES, J. BRUS, and M. F. SAUNERON
Gut Microbiota: The Neglected Endocrine Organ - Gerard Clarke, Roman M. Stilling, Paul J Kennedy, Catherine Stanton, John F. Cryan1, Timothy G. Dinan
The Gut Microbiome and the Brain - Leo Galland
Role of the normal gut microbiota - Sai Manasa Jandhyala, Rupjyoti Talukdar, Chivkula Subramanyam, Harish Vuyyuru, Mitnala Sasikala, D Nageshwar Reddy
Metabolism of Dietary and Microbial Vitamin B Family in the Regulation of Host Immunity - Ken Yoshii, Koji Hosomi, Kento Sawane1 and Jun Kunisawa
Interspecies Competition Impacts Targeted Manipulation of Human Gut Bacteria by Fiber-Derived Glycans - Michael L. Patnode, Zachary W. Beller, Nathan D. Han, Richard J. Giannone, Robert L. Hettich, Jeffrey I. Gordon
Metabolism of Dietary and Microbial Vitamin B Family in the Regulation of Host Immunity - Ken Yoshii, Koji Hosomi, Kento Sawane and Jun Kunisawa
Bifidobacteria or Fiber Protects against DietInduced Microbiota-Mediated Colonic Mucus Deterioration - Bjoern O. Schroeder, George M.H. Birchenough, Marcus Sta˚ hlman, Liisa Arike, Malin E.V. Johansson, Gunnar C. Hansson, Fredrik Backhed
Influence of diet on the gut microbiome and implications for human health - Rasnik K. Singh, Hsin‑Wen Chang, Di Yan, Kristina M. Lee, Derya Ucmak, Kirsten Wong, Michael Abrouk, Benjamin Farahnik, Mio Nakamura, Tian Hao Zhu, Tina Bhutani and Wilson Liao
Manipulating the Human Microbiome to Manage Disease - Catriona P. Harkins, MBChB, PhD, Heidi H. Kong, MD, MHS, Julia A. Segre, PhD
Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth - Victor Chedid, MD, Bani Chander Roland, MD, Edmundo Justino, MD
The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host - Qi Hui Sam, Matthew Wook Chang, and Louis Yi Ann Chai
Oral Candidal and Streptococcal carriage in Down syndrome patients - Gouse Mohiddin, Aravindha Babu Narayanaswamy, Masthan K. M. K., Anitha Nagarajan, Abikshyeet Panda, Shyam Sundar Behura
Small intestinal bacterial overgrowth syndrome in children - Katarzyna Siniewicz-Luzeńczyk1 , Agnieszka Bik-Gawin1 , Krzysztof Zeman1 , Leokadia Bąk-Romaniszyn2
Microbiome impact on metabolism and function of sex, thyroid, growth and parathyroid hormones - Michał Kunc1, Anna Gabrych1 and Jacek M. Witkowsk
Early Disruption of the Microbiome Leading to Decreased Antioxidant Capacity and Epigenetic Changes: Implications for the Rise in Autism - Rebecca S. Eshraghi, Richard C. Deth, Rahul Mittal, Mayank Aranke, Sae-In S. Kay, Baharak Moshiree and Adrien A. Eshraghi
The microbiota–gut–brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both? - Giada De Palma, Stephen M. Collins, Premysl Bercik and Elena F. Verdu
Gut microbiota: puppeteer of the host juvenile growth - Martin Schwarzer
Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication - Esther E. Fröhlich, Aitak Farzi, Raphaela Mayerhofer, Florian Reichmann, Angela Jacan, Bernhard Wagner, Erwin Zinser, Natalie Bordag , Christoph Magnes, Eleonore Fröhlich, Karl Kashofer, Gregor Gorkiewicz, Peter Holzer
Dysbiosis, small intestinal bacterial overgrowth and biofilms in autism and chronic illness - Anju Usman Singh
Blastocystis: how do specific diets and human gut microbiota affect its development and pathogenicity? - M. Lepczyńska1 & J. Białkowska2 & E. Dzika1 & K. Piskorz-Ogórek3,4 & J. Korycińska
GI Microbiota and Regulation of the Immune System - Edited by Gary B. Huffnagle and Mairi C. Noverr
Proton Pump Inhibitor Use in Infants: FDA Reviewer Experience - Ii-Lun Chen, Wen-Yi Gao, Aisha P. Johnson, Ali Niak, John Troiani, Joyce Korvick, Nancy Snow, Kristina Estes, Amy Taylor, and Donna Griebel
Inflammation and gastrointestinal Candida colonization - Carol A. Kumamoto
Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the Dawn of the Postantibiotic Era - Maria Kostakioti, Maria Hadjifrangiskou, and Scott J. Hultgren
Reduction in Obsessive Compulsive Disorder and Self-Injurious Behavior with Saccharomyces boulardii in a Child with Autism: A Case Report - Victoria Kobliner, MS, RDN; Elizabeth Mumper, MD, FAAP, IFMCP; Sidney M. Baker, MD
Motility Problems in the Intellectually Challenged Child, Adolescent, and Young Adult - Massimo Martinelli, MD, Annamaria Staiano, MD*
The Role of Fiber in the Treatment of Functional Gastrointestinal Disorders in Children - Cara Hannah Axelrod and Miguel Saps
Autism: Metabolism, Mitochondria, and the Microbiome - Derrick MacFabe, MD
Exposure to antibiotics in the first 24 months of life and neurocognitive outcomes at 11 years of age - R. F. Slykerman & C. Coomarasamy & K. Wickens & J. M. D. Thompson & T. V. Stanley & C. Barthow & J. Kang3 & J. Crane & E. A. Mitchell
- Gerard Clarke, Roman M. Stilling1, Paul J Kennedy, Catherine Stanton, John F. Cryan, Timothy G. Dinan
The Jarisch–Herxheimer Reaction After Antibiotic Treatment of Spirochetal Infections: A Review of Recent Cases and Our Understanding of Pathogenesis - Thomas Butler
A Study of Digestive Absorption in Four Cases of Down’s Syndrome. Down’s Syndrome, Malnutrition, Malabsorption, and Alzheimer’s Disease - F. ABALAN, A. JOUAN, M. T. WEERTS, C. SOLLES, J. BRUS, and M. F. SAUNERON
Gut Microbiota: The Neglected Endocrine Organ - Gerard Clarke, Roman M. Stilling, Paul J Kennedy, Catherine Stanton, John F. Cryan1, Timothy G. Dinan
The Gut Microbiome and the Brain - Leo Galland
Role of the normal gut microbiota - Sai Manasa Jandhyala, Rupjyoti Talukdar, Chivkula Subramanyam, Harish Vuyyuru, Mitnala Sasikala, D Nageshwar Reddy
Metabolism of Dietary and Microbial Vitamin B Family in the Regulation of Host Immunity - Ken Yoshii, Koji Hosomi, Kento Sawane1 and Jun Kunisawa
Interspecies Competition Impacts Targeted Manipulation of Human Gut Bacteria by Fiber-Derived Glycans - Michael L. Patnode, Zachary W. Beller, Nathan D. Han, Richard J. Giannone, Robert L. Hettich, Jeffrey I. Gordon
Metabolism of Dietary and Microbial Vitamin B Family in the Regulation of Host Immunity - Ken Yoshii, Koji Hosomi, Kento Sawane and Jun Kunisawa
Bifidobacteria or Fiber Protects against DietInduced Microbiota-Mediated Colonic Mucus Deterioration - Bjoern O. Schroeder, George M.H. Birchenough, Marcus Sta˚ hlman, Liisa Arike, Malin E.V. Johansson, Gunnar C. Hansson, Fredrik Backhed
Influence of diet on the gut microbiome and implications for human health - Rasnik K. Singh, Hsin‑Wen Chang, Di Yan, Kristina M. Lee, Derya Ucmak, Kirsten Wong, Michael Abrouk, Benjamin Farahnik, Mio Nakamura, Tian Hao Zhu, Tina Bhutani and Wilson Liao
Manipulating the Human Microbiome to Manage Disease - Catriona P. Harkins, MBChB, PhD, Heidi H. Kong, MD, MHS, Julia A. Segre, PhD
The Impact of Small Intestinal Bacterial Overgrowth on the Growth of Children and Adolescents - Alexandre Neves da Rocha Santos, Ana Cristina Fontenele Soares, Ricardo Palmero Oliveira, Mauro Batista de Morais
A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility - Mahesh S. Desai, Anna M. Seekatz, Nicole M. Koropatkin, Nobuhiko Kamada, Christina A. Hickey, Mathis Wolter, Nicholas A. Pudlo, Sho Kitamoto, Nicolas Terrapon, Arnaud Muller, Vincent B. Young, Bernard Henrissat, Paul Wilmes, Thaddeus S. Stappenbeck, Gabriel Núñez, and Eric C. Martens
A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility - Mahesh S. Desai, Anna M. Seekatz, Nicole M. Koropatkin, Nobuhiko Kamada, Christina A. Hickey, Mathis Wolter, Nicholas A. Pudlo, Sho Kitamoto, Nicolas Terrapon, Arnaud Muller, Vincent B. Young, Bernard Henrissat, Paul Wilmes, Thaddeus S. Stappenbeck, Gabriel Núñez, and Eric C. Martens
Bile/Gallbladder
Increased Risk of Symptomatic Gallbladder Disease in Adults With Down Syndrome - Carl V. Tyler Jr, Stephen J. Zyzanski and Lloyd Runser
Abdominal Ultrasound Scan in Down Syndrome Patients: High Frequency of Nonsymptomatic Biliary Tract Disease - Llerena JC Jr, Boy R, Barbosa Neto J, Vargas F, Fontana C, de Almeida JC, de Oliveira MC, Boechat PR, Mustacchi Z.
Cholelithiasis in Down’s syndrome - E Toscano, V Trivellini, G Andria
The interaction between bacteria and bile - Maire Begley, Cormac G.M. Gahan, Colin Hill
Endocrine functions of bile acids - Sander M Houten, Mitsuhiro Watanabe and Johan Auwerx
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation - Mitsuhiro Watanabe, Sander M. Houten, Chikage Mataki, Marcelo A. Christoffolete, Brian W. Kim, Hiroyuki Sato, Nadia Messaddeq, John W. Harney, Osamu Ezaki, Tatsuhiko Kodama, Kristina Schoonjans, Antonio C. Bianco & Johan Auwerx
Bile Formation and Secretion - James L. Boyer
The interaction between bacteria and bile - Maire Begley , Cormac G.M. Gahan, Colin Hill
Nutritional Approaches to Prevention and Treatment of Gallstones - Alan R. Gaby, MD
Cholelithiasis and biliary sludge in Down’s syndrome patients - Márcia Cristina Bastos Boëchat Kátia Silveira da Silva Juan Clinton Llerena Jr Paulo Roberto Mafra Boëchat
Abdominal Ultrasound Scan in Down Syndrome Patients: High Frequency of Nonsymptomatic Biliary Tract Disease - Llerena JC Jr, Boy R, Barbosa Neto J, Vargas F, Fontana C, de Almeida JC, de Oliveira MC, Boechat PR, Mustacchi Z.
Cholelithiasis in Down’s syndrome - E Toscano, V Trivellini, G Andria
The interaction between bacteria and bile - Maire Begley, Cormac G.M. Gahan, Colin Hill
Endocrine functions of bile acids - Sander M Houten, Mitsuhiro Watanabe and Johan Auwerx
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation - Mitsuhiro Watanabe, Sander M. Houten, Chikage Mataki, Marcelo A. Christoffolete, Brian W. Kim, Hiroyuki Sato, Nadia Messaddeq, John W. Harney, Osamu Ezaki, Tatsuhiko Kodama, Kristina Schoonjans, Antonio C. Bianco & Johan Auwerx
Bile Formation and Secretion - James L. Boyer
The interaction between bacteria and bile - Maire Begley , Cormac G.M. Gahan, Colin Hill
Nutritional Approaches to Prevention and Treatment of Gallstones - Alan R. Gaby, MD
Cholelithiasis and biliary sludge in Down’s syndrome patients - Márcia Cristina Bastos Boëchat Kátia Silveira da Silva Juan Clinton Llerena Jr Paulo Roberto Mafra Boëchat
Cholesterol
Role of cholesterol in parasitic infections - Devendra Bansal, Harinderpal Singh Bhatti and Rakesh Sehgal
The Effects of Cholesterol on Learning and Memory - The Effects of Cholesterol on Learning and Memory
Hypolipidemia: A Word of Caution - Elmehdawi RR
Cholesterol metabolism and homeostasis in the brain - Juan Zhang, Qiang Liu
The Effects of Cholesterol on Learning and Memory - The Effects of Cholesterol on Learning and Memory
Hypolipidemia: A Word of Caution - Elmehdawi RR
Cholesterol metabolism and homeostasis in the brain - Juan Zhang, Qiang Liu
Organic Acids
Organic Acid Concentrations in Amniotic Fluid Found in Normal and Down Syndrome Pregnancies Paddy Jim Baggot, Anna Jane Y. Eliseo, Nathaniel G. DeNicola, Jeremy A. Kalamarides, James D. Shoemaker
Role of plasma amino acids and urinary organic acids in diagnosis of mitochondrial diseases in children. - Shatla HM, Tomoum HY, Elsayed SM, Elagouza IA, Shatla RH, Mohsen MM, Hamed AN
Noninvasive urinary organic acids test to assess biochemical and nutritional individuality in autistic children - Kałużna-Czaplińska J
Urinary organic acids in infant malnutrition - Terán-García M1, Ibarra I, Velázquez A
Early identification of treatable inborn errors of metabolism in children with intellectual disability: The Treatable Intellectual Disability Endeavor protocol in British Columbia - Clara DM van Karnebeek MD PhD, Sylvia Stockler-Ipsiroglu MD PhD
Treatable inborn errors of metabolism presenting as cerebral palsy mimics: systematic literature review - Emma L Leach, Michael Shevell, Kristin Bowden, Sylvia Stockler-Ipsiroglu and Clara DM van Karnebeek
The In-Depth Evaluation of Suspected Mitochondrial Disease - Richard H. Haas, MB, BChir, MRCP, Sumit Parikh, MD, Marni J. Falk, MD, Russell P. Saneto, DO, PhD, Nicole I. Wolf, MD, Niklas Darin, MD, Lee-Jun Wong, PhD, Bruce H. Cohen, MD, and Robert K. Naviaux, MD, PhD
Role of plasma amino acids and urinary organic acids in diagnosis of mitochondrial diseases in children. - Shatla HM, Tomoum HY, Elsayed SM, Elagouza IA, Shatla RH, Mohsen MM, Hamed AN
Noninvasive urinary organic acids test to assess biochemical and nutritional individuality in autistic children - Kałużna-Czaplińska J
Urinary organic acids in infant malnutrition - Terán-García M1, Ibarra I, Velázquez A
Early identification of treatable inborn errors of metabolism in children with intellectual disability: The Treatable Intellectual Disability Endeavor protocol in British Columbia - Clara DM van Karnebeek MD PhD, Sylvia Stockler-Ipsiroglu MD PhD
Treatable inborn errors of metabolism presenting as cerebral palsy mimics: systematic literature review - Emma L Leach, Michael Shevell, Kristin Bowden, Sylvia Stockler-Ipsiroglu and Clara DM van Karnebeek
The In-Depth Evaluation of Suspected Mitochondrial Disease - Richard H. Haas, MB, BChir, MRCP, Sumit Parikh, MD, Marni J. Falk, MD, Russell P. Saneto, DO, PhD, Nicole I. Wolf, MD, Niklas Darin, MD, Lee-Jun Wong, PhD, Bruce H. Cohen, MD, and Robert K. Naviaux, MD, PhD
Vagus Nerve
The Versatile Role of the Vagus Nerve in the Gastrointestinal Tract - Nathalie Stakenborg, Martina Di Giovangiulio, Guy E. Boeckxstaens, Gianluca Matteoli
Transcutaneous Vagus Nerve Stimulation - Jens Ellrich
Transcutaneous Vagus Nerve Stimulation - Jens Ellrich
Carnitine
Role of carnitine in disease - Judith L Flanagan, Peter A Simmons, Joseph Vehige, Mark DP Willcox and Qian Garrett
The neurobiology of acetyl-L-carnitine - Giovanna Traina
Supplementation with carnitine reduces the severity of constipation: a retrospective study of patients with severe motor and intellectual disabilities - Shinya Murata,1,* Keisuke Inoue,1 Tomoki Aomatsu,2 Atsushi Yoden2 and Hiroshi Tamai
Carnitine Transport and Fatty Acid Oxidation - Nicola Longo1, Marta Frigeni, and Marzia Pasquali
Systemic primary carnitine deficiency: an overview of clinical manifestations, diagnosis, and management - Pilar L Magoulas1 and Ayman W El-Hattab
Unexpected awakening from comatose thyroid storm after a single intravenous injection of L-carnitine - Antoine Kimmoun, Gaittha Munagamage, Nicolas Dessalles, Alain Gerard, Francois Feillet and Bruno Levy
Acylcarnitines Reflecting or Inflicting Insulin Resistance? - Marieke G. Schooneman, Frédéric M. Vaz, Sander M. Houten and Maarten R. Soeters
The neurobiology of acetyl-L-carnitine - Giovanna Traina
Supplementation with carnitine reduces the severity of constipation: a retrospective study of patients with severe motor and intellectual disabilities - Shinya Murata,1,* Keisuke Inoue,1 Tomoki Aomatsu,2 Atsushi Yoden2 and Hiroshi Tamai
Carnitine Transport and Fatty Acid Oxidation - Nicola Longo1, Marta Frigeni, and Marzia Pasquali
Systemic primary carnitine deficiency: an overview of clinical manifestations, diagnosis, and management - Pilar L Magoulas1 and Ayman W El-Hattab
Unexpected awakening from comatose thyroid storm after a single intravenous injection of L-carnitine - Antoine Kimmoun, Gaittha Munagamage, Nicolas Dessalles, Alain Gerard, Francois Feillet and Bruno Levy
Acylcarnitines Reflecting or Inflicting Insulin Resistance? - Marieke G. Schooneman, Frédéric M. Vaz, Sander M. Houten and Maarten R. Soeters
Creatine
Lowering methylation demand by creatine supplementation paradoxically decreases DNA methylation - Youri E.C. Taes, Evy Bruggeman, Joachim Bleys and Joris R. Delanghe
Creatine Supplementation - Matthew Hall, DO and Thomas H. Trojian, MD, FACSM
Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate - Lori M. Stead, Keegan P. Au, Rene´ L. Jacobs, Margarte E. Brosnan, and John T. Brosnan
Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial - Caroline Rae, Alison L. Digney, Sally R. McEwan and Timothy C. Bates
Creatine Supplementation - Matthew Hall, DO and Thomas H. Trojian, MD, FACSM
Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate - Lori M. Stead, Keegan P. Au, Rene´ L. Jacobs, Margarte E. Brosnan, and John T. Brosnan
Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial - Caroline Rae, Alison L. Digney, Sally R. McEwan and Timothy C. Bates
Aluminum
Aluminium in brain tissue in autism - Matthew Molda, Dorcas Umarb, Andrew Kingc, Christopher Exley
Aluminum in Childhood Vaccines Is Unsafe - Neil Z. Miller
Autism & Aluminum Adjuvants in Vaccines - Informed Consent Action Network
Reconsideration of the immunotherapeutic pediatric safe dose levels of aluminum - James Lyons-Weilera, Robert Ricketson
Infants’ exposure to aluminum from vaccines and breast milk during the first 6 months - José G. Dórea and Rejane C. Marques
The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what could be the mechanisms involved? - Gerwyn Morris, Basant K. Puri and Richard E. Frye
Aluminum in Childhood Vaccines Is Unsafe - Neil Z. Miller
Autism & Aluminum Adjuvants in Vaccines - Informed Consent Action Network
Reconsideration of the immunotherapeutic pediatric safe dose levels of aluminum - James Lyons-Weilera, Robert Ricketson
Infants’ exposure to aluminum from vaccines and breast milk during the first 6 months - José G. Dórea and Rejane C. Marques
The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what could be the mechanisms involved? - Gerwyn Morris, Basant K. Puri and Richard E. Frye
Mitochondria
Coenzyme Q10: The essential nutrient - Rajiv Saini
Mitochondria as a therapeutic target for common pathologies - Michael P. Murphy and Richard C. Hartley
A Modern Approach to the Treatment of Mitochondrial Disease - Sumit Parikh, MD, Russell Saneto, DO, PhD, Marni J. Falk, MD, Irina Anselm, MD, Bruce H. Cohen, MD, Richard Haas, MB, BChir, MRCP, and The Mitochondrial Medicine Society
Mitochondrial function and toxicity: Role of the B vitamin family on mitochondrial energy metabolism - Flore Depeint, W. Robert Bruce, Nandita Shangari, Rhea Mehta, Peter J. O’Brien
The Brain's Reliance on Glucose Metabolism and Mitochondria Function - Erica Peirson, ND
Mitochondria as a therapeutic target for common pathologies - Michael P. Murphy and Richard C. Hartley
A Modern Approach to the Treatment of Mitochondrial Disease - Sumit Parikh, MD, Russell Saneto, DO, PhD, Marni J. Falk, MD, Irina Anselm, MD, Bruce H. Cohen, MD, Richard Haas, MB, BChir, MRCP, and The Mitochondrial Medicine Society
Mitochondrial function and toxicity: Role of the B vitamin family on mitochondrial energy metabolism - Flore Depeint, W. Robert Bruce, Nandita Shangari, Rhea Mehta, Peter J. O’Brien
The Brain's Reliance on Glucose Metabolism and Mitochondria Function - Erica Peirson, ND
MicroRNA
Expression of miR-132 in Down syndrome subjects - Michele Salemi, Concetta Barone, Maria Grazia Salluzzo, Mariaconcetta Giambirtone, Federico Ridolfo, Corrado Romano
MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID, and Fragile X syndrome - Wei-Hong Siew, Kai-Leng Tan, Maryam Abbaspour Babaei, Pike-See Cheah and King-Hwa Ling
Boosting the Brain’s Ability to Block Inflammation via MicroRNA-132 - Luke A.J. O’Neill
MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase - Iftach Shaked, Ari Meerson, Yochai Wolf, Ran Avni, David Greenberg, Adi Gilboa-Geffen, and Hermona Soreq
Advances in Roles of miR-132 in the Nervous System - Yun Qian1, Jialin Song1, Yuanming Ouyang1, Qixin Han, Wei Chen1, Xiaotian Zhao, Yangmei Xie, Yinghui Chen, Weien Yuan and Cunyi Fan
miR-132 inhibits lipopolysaccharide-induced inflammation in alveolar macrophages by the cholinergic anti-inflammatory pathway - Fen Liu, Yong Li, Rong Jiang, Cheng Nie, Zhenguo Zeng, Ning Zhao, Caixue Huang, Qiang Shao, Chengzhi Ding, Cheng Qing, Liang Xia, Erming Zeng, and Kejian Qian
Down syndrome and microRNAs (Review) - ALDINA BRÁS, ANTÓNIO S. RODRIGUES, BRUNO GOMES and JOSÉ RUEFF
MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID, and Fragile X syndrome - Wei-Hong Siew, Kai-Leng Tan, Maryam Abbaspour Babaei, Pike-See Cheah and King-Hwa Ling
Boosting the Brain’s Ability to Block Inflammation via MicroRNA-132 - Luke A.J. O’Neill
MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase - Iftach Shaked, Ari Meerson, Yochai Wolf, Ran Avni, David Greenberg, Adi Gilboa-Geffen, and Hermona Soreq
Advances in Roles of miR-132 in the Nervous System - Yun Qian1, Jialin Song1, Yuanming Ouyang1, Qixin Han, Wei Chen1, Xiaotian Zhao, Yangmei Xie, Yinghui Chen, Weien Yuan and Cunyi Fan
miR-132 inhibits lipopolysaccharide-induced inflammation in alveolar macrophages by the cholinergic anti-inflammatory pathway - Fen Liu, Yong Li, Rong Jiang, Cheng Nie, Zhenguo Zeng, Ning Zhao, Caixue Huang, Qiang Shao, Chengzhi Ding, Cheng Qing, Liang Xia, Erming Zeng, and Kejian Qian
Down syndrome and microRNAs (Review) - ALDINA BRÁS, ANTÓNIO S. RODRIGUES, BRUNO GOMES and JOSÉ RUEFF
Herbs
Neuropharmacological Review of the Nootropic Herb Bacopa monnieri - Sebastian Aguiar and Thomas Borowski
A review on therapeutic potential of Nigella sativa: A miracle herb - Aftab Ahmad, Asif Husain, Mohd Mujeeb, Shah Alam Khan, Abul Kalam Najmi, Nasir Ali Siddique, Zoheir A. Damanhouri, Firoz Anwar
Neuropharmacological effects of Nigella sativa - Farimah Beheshti, Majid Khazaei, Mahmoud Hosseini
A Compound Herbal Preparation (CHP) in the Treatment of Children With ADHD: A Randomized Controlled Trial - M. Katz, A. Adar Levine, H. Kol-Degani, and L. Kav-Venaki
Efficacy of Standardized Extract of Bacopa monnieri (Bacognize„) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial - Navneet Kumar, L. G. Abichandani, Vijay Thawani, K. J. Gharpure, M. U. R. Naidu, and G. Venkat Ramana
Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A Systematic Review and Meta-analysis - Panupong Puttarak, Piyameth Dilokthornsakul, Surasak Saokaew, Teerapon Dhippayom, Chuenjid Kongkaew, Rosarin Sruamsiri, Anchalee Chuthaputti & Nathorn Chaiyakunapruk
Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all - KASHMIRA J. GOHIL, JAGRUTI A. PATEL AND ANURADHA K. GAJJAR
Effect of ginger on gastric motility and symptoms of functional dyspepsia - Ming-Luen Hu, Christophan K Rayner, Keng-Liang Wu, Seng-Kee Chuah, Wei-Chen Tai, Yeh-Pin Chou, Yi-Chun Chiu, King-Wah Chiu, Tsung-Hui Hu
Ginger in gastrointestinal disorders: A systematic review of clinical trials - Mehrnaz Nikkhah Bodagh, Iradj Maleki, Azita Hekmatdoost
Effects of Ginger Constituents on the Gastrointestinal Tract: Role of Cholinergic M3 and Serotonergic 5-HT3 and 5-HT4 Receptors - Heinz H. Pertz, Jochen Lehmann, René Roth-Ehrang, Sigurd Elz
The Amazing and Mighty Ginger - Ann M. Bode and Zigang Dong
Larch Arabinogalactan: Clinical Relevance of a Novel Immune-Enhancing Polysaccharide - Gregory S. Kelly, N.D.
Compounding Herbal Medicine for the Treatment of Drug Resistant Bacteria - Tiffany Wyse, N.D.
A review on therapeutic potential of Nigella sativa: A miracle herb - Aftab Ahmad, Asif Husain, Mohd Mujeeb, Shah Alam Khan, Abul Kalam Najmi, Nasir Ali Siddique, Zoheir A. Damanhouri, Firoz Anwar
Neuropharmacological effects of Nigella sativa - Farimah Beheshti, Majid Khazaei, Mahmoud Hosseini
A Compound Herbal Preparation (CHP) in the Treatment of Children With ADHD: A Randomized Controlled Trial - M. Katz, A. Adar Levine, H. Kol-Degani, and L. Kav-Venaki
Efficacy of Standardized Extract of Bacopa monnieri (Bacognize„) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial - Navneet Kumar, L. G. Abichandani, Vijay Thawani, K. J. Gharpure, M. U. R. Naidu, and G. Venkat Ramana
Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A Systematic Review and Meta-analysis - Panupong Puttarak, Piyameth Dilokthornsakul, Surasak Saokaew, Teerapon Dhippayom, Chuenjid Kongkaew, Rosarin Sruamsiri, Anchalee Chuthaputti & Nathorn Chaiyakunapruk
Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all - KASHMIRA J. GOHIL, JAGRUTI A. PATEL AND ANURADHA K. GAJJAR
Effect of ginger on gastric motility and symptoms of functional dyspepsia - Ming-Luen Hu, Christophan K Rayner, Keng-Liang Wu, Seng-Kee Chuah, Wei-Chen Tai, Yeh-Pin Chou, Yi-Chun Chiu, King-Wah Chiu, Tsung-Hui Hu
Ginger in gastrointestinal disorders: A systematic review of clinical trials - Mehrnaz Nikkhah Bodagh, Iradj Maleki, Azita Hekmatdoost
Effects of Ginger Constituents on the Gastrointestinal Tract: Role of Cholinergic M3 and Serotonergic 5-HT3 and 5-HT4 Receptors - Heinz H. Pertz, Jochen Lehmann, René Roth-Ehrang, Sigurd Elz
The Amazing and Mighty Ginger - Ann M. Bode and Zigang Dong
Larch Arabinogalactan: Clinical Relevance of a Novel Immune-Enhancing Polysaccharide - Gregory S. Kelly, N.D.
Compounding Herbal Medicine for the Treatment of Drug Resistant Bacteria - Tiffany Wyse, N.D.
Anesthesia
Anesthetic Considerations in Patients with Mitochondrial Defects - Julie Niezgoda, Phil G Morgan
Mitochondrial Diseases and Anesthesia: A Literature Review of Current Opinions - MAJ Berenice Rivera-Cruz, CRNA, DNAP, USAR
Mitochondrial Diseases and Anesthesia: A Literature Review of Current Opinions - MAJ Berenice Rivera-Cruz, CRNA, DNAP, USAR
Autoimmune
Down syndrome and coexistent autoimmune diseases - Dimitry Chistiakov
A concise review of Hashimoto thyroiditis (HT) and the importance of iodine, selenium, vitamin D and gluten on the autoimmunity and dietary management of HT patients. - Michael I. Liontiris, MD, Elias E. Mazokopakis MD, PhD
Marked improvement of thyroid function and autoimmunity by Aloe barbadensis miller juice in patients with subclinical hypothyroidism - Daniela Metroa, Valeria Cernarob, Mattia Papaa, Salvatore Benvenga
Anti-parietal cell antibodies-diagnostic significance - Ewa Rusak, Agata Chobot, Agnieszka Krzywicka, Janet Wenzlau
Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases - Maria C. Opazo, Elizabeth M. Ortega-Rocha, Irenice Coronado-Arrázola, Laura C. Bonifaz, Helene Boudin, Michel Neunlist, Susan M. Bueno, Alexis M. Kalergis, and Claudia A. Riedel
Hyperthyroidism in Down’s Syndrome – A Report of Two Cases - Uma Kaimal Saikia and Bipul Kumar Choudhury
Leaky Gut As a Danger Signal for Autoimmune Diseases - Qinghui Mu, Jay Kirby, Christopher M. Reilly and Xin M. Luo
Autoimmunity and the Gut - Andrew W. Campbell
Molecular Mimicry as a Mechanism of Autoimmune Disease - Matthew F. Cusick, PhD, Jane E. Libbey, MS, and Robert S. Fujinami, PhD
Commensal Bacteria Regulate Thymic Aire Expression - Akihito Nakajima, Naoko Negishi, Hiromichi Tsurui, Naomi Kadowaki-Ohtsuji, Keiko Maeda, Masanobu Nanno, Yoshitaka Yamaguchi, Nobuyoshi Shimizu, Hideo Yagita, Ko Okumura, Sonoko Habu
Vaccine-induced autoimmunity: the role of molecular mimicry and immune crossreaction - Yahel Segal and Yehuda Shoenfeld
Infection, vaccines and other environmental triggers of autoimmunity - Vered Molina & Yehuda Shoenfeld
Mast Cell and Autoimmune Diseases - Yunzhi Xu and Guangjie Chen
Histamine, Immune Cells and Autoimmunity - Elke Schneider, Maria Leite-de-Moraes and Michel Dy
Does Akkermansia muciniphila play a role in type 1 diabetes? - Gilles Mithieux
Fish Oil
How does high DHA fish oil affect health? A systematic review of evidence - Samaneh Ghasemi Farda, Fenglei Wangc, Andrew J. Sinclaira, Glenn Elliottb, and Giovanni M. Turchinid
Brain Health across the Lifespan: A Systematic Review on the Role of Omega-3 Fatty Acid Supplements - Emma Derbyshire
Brain Health across the Lifespan: A Systematic Review on the Role of Omega-3 Fatty Acid Supplements - Emma Derbyshire
Thyroid
Effects of Long-Term Combination LT4 and LT3 Therapy for Improving Hypothyroidism and Overall Quality of Life - Anam Tariq, DO, Yijin Wert, MS, Pramil Cheriyath, MD, and Renu Joshi, MD
Applying a systems approach to thyroid physiology: Looking at the whole with a mitochondrial perspective instead of judging single TSH values or why we should know more about mitochondria to understand metabolism - Roy Moncayo , Helga Moncayo
Down syndrome and thyroid dysfunction: Should nutritional support be the first-line treatment? - R. Thiel, Steven Wm. Fowkes
Applying a systems approach to thyroid physiology: Looking at the whole with a mitochondrial perspective instead of judging single TSH values or why we should know more about mitochondria to understand metabolism - Roy Moncayo , Helga Moncayo
Down syndrome and thyroid dysfunction: Should nutritional support be the first-line treatment? - R. Thiel, Steven Wm. Fowkes
Sleep
Cognitive and Behavioral Consequences of Sleep Disordered Breathing in Children - Irina Trosman, and Samuel J.
A review of sleep disorders and melatonin - Zizhen Xie, Fei Chen, William A. Li, Xiaokun Geng, Changhong Li, Xiaomei Meng, Yan Feng, Wei Liu & Fengchun Yu Trosman
Sleep and sleep disordered breathing in children with Down syndrome: effects on behaviour, neurocognition and the cardiovascular system - Rosemary SC. Horne, Poornima Wijayaratne, Gillian M. Nixon, Lisa M. Walter
Crosstalk between metabolism and circadian clocks - Hans Reinke and Gad Asher
The effect of mode of breathing on craniofacial growth — revisited - Timo Peltomäki
GABA and L-theanine mixture decreases sleep latency and improves NREM sleep - Suhyeon Kima, Kyungae Joa, Ki-Bae Hongb, Sung Hee Hanc and Hyung Joo Suh
A review of sleep disorders and melatonin - Zizhen Xie, Fei Chen, William A. Li, Xiaokun Geng, Changhong Li, Xiaomei Meng, Yan Feng, Wei Liu & Fengchun Yu Trosman
Sleep and sleep disordered breathing in children with Down syndrome: effects on behaviour, neurocognition and the cardiovascular system - Rosemary SC. Horne, Poornima Wijayaratne, Gillian M. Nixon, Lisa M. Walter
Crosstalk between metabolism and circadian clocks - Hans Reinke and Gad Asher
The effect of mode of breathing on craniofacial growth — revisited - Timo Peltomäki
GABA and L-theanine mixture decreases sleep latency and improves NREM sleep - Suhyeon Kima, Kyungae Joa, Ki-Bae Hongb, Sung Hee Hanc and Hyung Joo Suh
Histamine
Histamine and histamine intolerance - Laura Maintz and Natalija Novak
Histamine Intolerance in Clinical Practice - Laura Maintz, Thomas Bieber, Natalija Novak
Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease - Seong Hwan Kima , Nigel Cairnsb , Michael Fountoulakiscc , Gert Lubec
Similar deficits of central histaminergic system in patients with Down syndrome and Alzheimer disease - Christoph Schneidera , Daniele Risserb, Liselotte Kirchner a , Erwin Kitzmu¨ller,a , Nigel Cairnsc , Helmut Prastd, Nicolas Singewaldd, Gert Lubec
Human brain cytosolic histamine-N-methyltransferase is decreased in Down syndrome and increased in Pick’s disease - Seong Hwan Kima , Kurt Krapfenbauerb , Myeong Sook Cheona , Michael Fountoulakisb , Nigel J. Cairnsc , Gert Lubec
Histamine N-Methyltransferase in the Brain - Takeo Yoshikawa , Tadaho Nakamura and Kazuhiko Yanai
Histamine in the Regulation of Wakefulness - Mahesh M. Thakkar
Histamine in the brain: Beyond sleep and memory - Maria Beatrice Passani, Patrizia Giannoni, Corrado Bucherelli, Elisabetta Baldi, Patrizio Blandina
Histamine in Neurotransmission and Brain Diseases - Saara Nuutinen and Pertti Panula
Histamine N-methyltransferase regulates aggression and the sleepwake cycle - Fumito Naganuma, Tadaho Nakamura, Takeo Yoshikawa, Tomomitsu Iida, Yamato Miura, Anikó Kárpáti, Takuro Matsuzawa, Atushi Yanai, Asuka Mogi, Takatoshi Mochizuki, Nobuyuki Okamura & Kazuhiko Yanai
Histamine and Other Biogenic Amines in Food. From Scombroid Poisoning to Histamine Intolerance - Oriol Comas-Basté, Maria Luz Latorre-Moratalla, Sònia Sánchez-Pérez, Maria Teresa Veciana-Nogués and Maria del Carmen Vidal-Carou
MICROBIAL PATTERNS IN PATIENTS WITH HISTAMINE INTOLERANCE - M. SCHINK, P.C. KONTUREK, E. TIETZ, W. DIETERICH, T.C. PINZER, S. WIRTZ, M.F. NEURATH, Y. ZOPF
Thyroid Hormone, Thyroid Hormone Metabolites and Mast Cells: A Less Explored Issue - Elisa Landucci, Annunziatina Laurino, Lorenzo Cinci, Manuela Gencarelli and Laura Raimondi
Histamine Intolerance in Clinical Practice - Laura Maintz, Thomas Bieber, Natalija Novak
Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease - Seong Hwan Kima , Nigel Cairnsb , Michael Fountoulakiscc , Gert Lubec
Similar deficits of central histaminergic system in patients with Down syndrome and Alzheimer disease - Christoph Schneidera , Daniele Risserb, Liselotte Kirchner a , Erwin Kitzmu¨ller,a , Nigel Cairnsc , Helmut Prastd, Nicolas Singewaldd, Gert Lubec
Human brain cytosolic histamine-N-methyltransferase is decreased in Down syndrome and increased in Pick’s disease - Seong Hwan Kima , Kurt Krapfenbauerb , Myeong Sook Cheona , Michael Fountoulakisb , Nigel J. Cairnsc , Gert Lubec
Histamine N-Methyltransferase in the Brain - Takeo Yoshikawa , Tadaho Nakamura and Kazuhiko Yanai
Histamine in the Regulation of Wakefulness - Mahesh M. Thakkar
Histamine in the brain: Beyond sleep and memory - Maria Beatrice Passani, Patrizia Giannoni, Corrado Bucherelli, Elisabetta Baldi, Patrizio Blandina
Histamine in Neurotransmission and Brain Diseases - Saara Nuutinen and Pertti Panula
Histamine N-methyltransferase regulates aggression and the sleepwake cycle - Fumito Naganuma, Tadaho Nakamura, Takeo Yoshikawa, Tomomitsu Iida, Yamato Miura, Anikó Kárpáti, Takuro Matsuzawa, Atushi Yanai, Asuka Mogi, Takatoshi Mochizuki, Nobuyuki Okamura & Kazuhiko Yanai
Histamine and Other Biogenic Amines in Food. From Scombroid Poisoning to Histamine Intolerance - Oriol Comas-Basté, Maria Luz Latorre-Moratalla, Sònia Sánchez-Pérez, Maria Teresa Veciana-Nogués and Maria del Carmen Vidal-Carou
MICROBIAL PATTERNS IN PATIENTS WITH HISTAMINE INTOLERANCE - M. SCHINK, P.C. KONTUREK, E. TIETZ, W. DIETERICH, T.C. PINZER, S. WIRTZ, M.F. NEURATH, Y. ZOPF
Thyroid Hormone, Thyroid Hormone Metabolites and Mast Cells: A Less Explored Issue - Elisa Landucci, Annunziatina Laurino, Lorenzo Cinci, Manuela Gencarelli and Laura Raimondi
Alopecia
The Role of Vitamins and Minerals in Hair Loss: A Review - Hind M. Almohanna . Azhar A. Ahmed . John P. Tsatalis . Antonella Tosti
Alopecia areata and the gut –the link opens up for novel therapeutic interventions - Annika Borde & Annika Åstrand
Alopecia areata: A multifactorial autoimmune condition - Teontor Simakoua, John P. Butcherb, Stuart Reidc, Fiona L. Henriquez
Alopecia areata and the gut –the link opens up for novel therapeutic interventions - Annika Borde & Annika Åstrand
Alopecia areata: A multifactorial autoimmune condition - Teontor Simakoua, John P. Butcherb, Stuart Reidc, Fiona L. Henriquez
Nature/Green Spaces
Road proximity, air pollution, noise, green space and neurologic disease incidence: a population-based cohort study - Weiran Yuchi, Hind Sbihi, Hugh Davies, Lillian Tamburic and Michael Brauer
A Review of the Benefits of Nature Experiences: More Than Meets the Eye - Lara S. Franco, Danielle F. Shanahan and Richard A. Fuller
A Review of the Benefits of Nature Experiences: More Than Meets the Eye - Lara S. Franco, Danielle F. Shanahan and Richard A. Fuller
Uncategorized
Bridging the Gap Between Physical Health and Autism Spectrum Disorder - Regina Sala, Lorene Amet, Natasa Blagojevic-Stokic, Paul Shattock and Paul Whiteley
Significance of Low Plasma Homocysteine - Richard S. Lord, Ph.D. and Kara Fitzgerald, N.D.
Sulfate and Sulfation - R.H. Waring
Impaired Sulfate Metabolism and Epigenetics: Is There a Link in Autism? - Samantha Hartzell and Stephanie Seneff
Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets - Rafael Lugo-Huitrón, Perla Ugalde Muñiz, Benjamin Pineda, José Pedraza-Chaverrí, Camilo Ríos and Verónica Pérez-de la Cruz
Sugar for the brain: the role of glucose in physiological and pathological brain function - Philipp Mergenthaler, Ute Lindauer, Gerald A. Dienel, and Andreas Meisel
Feeding Our Immune System: Impact on Metabolism - Isabelle Wolowczuk, Claudie Verwaerde, Odile Viltart, Anne Delanoye, Myriam Delacre, Bruno Pot, and Corinne Grangette
Relationship between the use of lower extremity orthoses and the developmental quotient of The Kyoto Scale of Psychological Development in children with Down syndrome - Yoshihide Kanai, RPT, PhD, Hirotaka Mutsuzaki, MD, PhD, Tomohiro Nakayama, MD, PhD, Arito Yozu, MD, PhD, Nobuaki Iwasaki, MD, PhD
Clinical Factors Associated with PANDAS - Tanya K. Murphy, MD, Eric A. Storch, PhD, Adam B. Lewin, PhD., Paula J. Edge, BS., and Wayne K. Goodman, MD
More severe intellectual disability was found in teenagers than younger children with Down syndrome - ULRIKA WESTER OXELGREN1, ÅSA MYRELID, GÖRAN ANNERÉN, JOAKIM WESTERLUND, JAN GUSTAFSSON, ELISABETH FERNELL
Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer’s disease in adults with Down syndrome: implications for the intellectual disability population - V. P. Prasher
Diet and Alzheimer’s Dementia – Nutritional Approach to Modulate Inflammation - Katarzyna Szczechowiaka , Breno S. Dinizb , Jerzy Leszek
A specific protocol of myo-functional therapy in children with Down syndrome. A pilot study - S. Saccomanno, C. Martini, L. D’Alatri, S. Farina, C. Grippaudo
Motor Stereotypies - Harvey S. Singer, MD
Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases - Marilia Brito Gomes and Carlos Antonio Negrato
The Physiological Action of Picolinic Acid in the Human Brain - R.S. Grant, S.E. Coggan and G.A. Smythe
Down Syndrome, Ageing and Epigenetics - Noémie Gensous, Claudio Franceschi, Stefano Salvioli, Paolo Garagnani, and Maria Giulia Bacalini
Metabolic features of the cell danger response - Robert K. Naviaux
Baby shampoo nasal irrigations for the symptomatic post–functional endoscopic sinus surgery patient - Alexander G. Chiu, M.D., James N. Palmer, M.D., Bradford A. Woodworth, M.D., Laurel Doghramji, R.N., Michael B. Cohen, B.A., Anthony Prince, B.A., and Noam A. Cohen, M.D., Ph.D.
Audit on Cow's Milk Protein Intolerance in Children with Down Syndrome - N Nallapeta, K Clarke, S Puri
Having a Son or Daughter with Down Syndrome: Perspectives from Mothers and Fathers - Brian G. Skotko, Susan P. Levine, and Richard Goldstein
Translating translation in Down syndrome - Mark Halliday and Giovanna R. Mallucci
Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome - Ping Jun Zhu, Sanjeev Khatiwada, Ya Cui, Lucas C. Reineke1, Sean W. Dooling, Jean J. Kim, Wei Li, Peter Walter, Mauro Costa-Mattioli
Role of Reactive Oxygen Species in Mast Cell Degranulation - M. A. Chelombitko, A. V. Fedorov, O. P. Ilyinskaya, R. A. Zinovkin, and B. V. Chernyak
Role of Oxidants in Mast Cell Activation - Yoshihiro Suzuki, Tetsuro Yoshimaru, Toshio Inoue, Osamu Niide, Chisei Ra
Potential natural compounds for preventing 2019-nCoV infection - Hansen Chen, Qiaohui Du
Diet in hidradenitis suppurativa: a review of published and lay literature - Annika Silfvast-Kaiser, MD , Ronnie Youssef, BS, and So Y. Paek, MD
Parental Ratings of Behavioral Effects of Biomedical Interventions - Autism Research Institute
Significance of Low Plasma Homocysteine - Richard S. Lord, Ph.D. and Kara Fitzgerald, N.D.
Sulfate and Sulfation - R.H. Waring
Impaired Sulfate Metabolism and Epigenetics: Is There a Link in Autism? - Samantha Hartzell and Stephanie Seneff
Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets - Rafael Lugo-Huitrón, Perla Ugalde Muñiz, Benjamin Pineda, José Pedraza-Chaverrí, Camilo Ríos and Verónica Pérez-de la Cruz
Sugar for the brain: the role of glucose in physiological and pathological brain function - Philipp Mergenthaler, Ute Lindauer, Gerald A. Dienel, and Andreas Meisel
Feeding Our Immune System: Impact on Metabolism - Isabelle Wolowczuk, Claudie Verwaerde, Odile Viltart, Anne Delanoye, Myriam Delacre, Bruno Pot, and Corinne Grangette
Relationship between the use of lower extremity orthoses and the developmental quotient of The Kyoto Scale of Psychological Development in children with Down syndrome - Yoshihide Kanai, RPT, PhD, Hirotaka Mutsuzaki, MD, PhD, Tomohiro Nakayama, MD, PhD, Arito Yozu, MD, PhD, Nobuaki Iwasaki, MD, PhD
Clinical Factors Associated with PANDAS - Tanya K. Murphy, MD, Eric A. Storch, PhD, Adam B. Lewin, PhD., Paula J. Edge, BS., and Wayne K. Goodman, MD
More severe intellectual disability was found in teenagers than younger children with Down syndrome - ULRIKA WESTER OXELGREN1, ÅSA MYRELID, GÖRAN ANNERÉN, JOAKIM WESTERLUND, JAN GUSTAFSSON, ELISABETH FERNELL
Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer’s disease in adults with Down syndrome: implications for the intellectual disability population - V. P. Prasher
Diet and Alzheimer’s Dementia – Nutritional Approach to Modulate Inflammation - Katarzyna Szczechowiaka , Breno S. Dinizb , Jerzy Leszek
A specific protocol of myo-functional therapy in children with Down syndrome. A pilot study - S. Saccomanno, C. Martini, L. D’Alatri, S. Farina, C. Grippaudo
Motor Stereotypies - Harvey S. Singer, MD
Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases - Marilia Brito Gomes and Carlos Antonio Negrato
The Physiological Action of Picolinic Acid in the Human Brain - R.S. Grant, S.E. Coggan and G.A. Smythe
Down Syndrome, Ageing and Epigenetics - Noémie Gensous, Claudio Franceschi, Stefano Salvioli, Paolo Garagnani, and Maria Giulia Bacalini
Metabolic features of the cell danger response - Robert K. Naviaux
Baby shampoo nasal irrigations for the symptomatic post–functional endoscopic sinus surgery patient - Alexander G. Chiu, M.D., James N. Palmer, M.D., Bradford A. Woodworth, M.D., Laurel Doghramji, R.N., Michael B. Cohen, B.A., Anthony Prince, B.A., and Noam A. Cohen, M.D., Ph.D.
Audit on Cow's Milk Protein Intolerance in Children with Down Syndrome - N Nallapeta, K Clarke, S Puri
Having a Son or Daughter with Down Syndrome: Perspectives from Mothers and Fathers - Brian G. Skotko, Susan P. Levine, and Richard Goldstein
Translating translation in Down syndrome - Mark Halliday and Giovanna R. Mallucci
Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome - Ping Jun Zhu, Sanjeev Khatiwada, Ya Cui, Lucas C. Reineke1, Sean W. Dooling, Jean J. Kim, Wei Li, Peter Walter, Mauro Costa-Mattioli
Role of Reactive Oxygen Species in Mast Cell Degranulation - M. A. Chelombitko, A. V. Fedorov, O. P. Ilyinskaya, R. A. Zinovkin, and B. V. Chernyak
Role of Oxidants in Mast Cell Activation - Yoshihiro Suzuki, Tetsuro Yoshimaru, Toshio Inoue, Osamu Niide, Chisei Ra
Potential natural compounds for preventing 2019-nCoV infection - Hansen Chen, Qiaohui Du
Diet in hidradenitis suppurativa: a review of published and lay literature - Annika Silfvast-Kaiser, MD , Ronnie Youssef, BS, and So Y. Paek, MD
Parental Ratings of Behavioral Effects of Biomedical Interventions - Autism Research Institute